Yes, cork flooring can be used effectively in a basement setting with a moisture barrier. Concrete basement slabs are prone to moisture migration, which can damage the flooring when a moisture barrier is not installed. 

For glue-down flooring, we recommend installing a moisture barrier, then a subfloor, before installing the glue-down cork flooring.

For floating flooring, a subfloor is not required; the tiles can be installed directly on the moisture barrier.